Европейский журнал экспериментальной биологии Открытый доступ

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Effect of dexamethasone in reducing headache after spinal anesthesia in Cesarean section

Arazberdi Ghochae, Amin Hasanzad, Kazem Kazemnezhad and Seyed Ali Mousavi Mohajer

Spinal anesthesia causes headache in1%-15% of patients undergoing caesarean section. A several techniques and materials have been tried to minimize spinal anesthesia–induced headache, with variable results. We compared the efficacy of pretreatment with 0.2 mg/kg dexamethasone before spinal anesthesia for prevention of headache. 100 adult patients, undergoing caesarean section were randomly assigned into 2 groups of 50. Group 1 received normal saline, group 2 received 0.2 mg/kg dexamethasone Headache was assessed with a four-point scale: 0 = no pain, 1 & 2 & 3 = mild pain, 4 & 5 & 6 & 7 = moderate pain, and 8 & 9 & 10 = severe pain, after caesarean section. In the first group 42 patients (84 %) had no pain and in the second group 47 patients (94%) had no pain. It was not statistically significant (P-value> 0.05). Pretreatment with dexamethasone doesn’t prevent of headache associated with spinal anesthesia in patients undergoing caesarean section. We therefore don’t suggest routine pretreatment with dexamethasone.