A.K. Umera Begam, N. Manoharan, J. Sirajudeen, A. Abdul Jameel
The antimicrobial activity of ethanolic plant extracts (Ocimum sanctum, Thespesia populnea and Pongamia glabra) were studied against three bacterial and one fungal organisms. The bacterial species include two Gram-positive(Streptococcus sp. and Staphylococcus aureus) and one Gram-negative(Escherichia coli). Aspergillus niger is the fungus taken for the study. In this study, the antimicrobial potency of single plants and the combined extracts, against the above mentioned microorganisms were assessed by well-diffusion technique. The plant extracts were subjected to various preliminary phytochemical analyses to determine the phytochemical constituents present in them. Studies revealed that, the synergism is more marked against Streptococcus spp. and Aspergillus niger especially the combination of Thespesia populnea and Ocimum sanctum is found to have more potent microbicidal activity.