Savita Krishnamurthy*, Debasree Gangopadhyay, Mahua Roy, Rhitajyoti Sengupta, Souvik Dutta
Objective: The study aims to assess feasibility of transcatheter device closure of patent ductus arteriosus in infants weighing less than 5 kg and retrospectively compares the result with the age and weight matched surgical duct ligation group.
Methods: Twenty infants weighing less than 5 kg underwent device closure of patent ductus arteriosus between January 2017 to May 2019. The result was compared with retrospective data from twenty other infants who under went surgical duct ligation.
Results: The patients were divided in two groups, Group A the device closure group and Group B the surgical ligation group. Within Group A, twenty infants with a mean age of 6.5 ± 2.4 months, mean weight of 4.32 ± 0.84 kg and mean ductal diameter 3.96 ± 1.38 mm underwent device closure. The mean age of patients in the surgical group was 5.6 ± 3.5 months, mean weight 3.48 ± 1.26 kg and the mean duct diameter 4.72 ± 1.94 mm. Follow up duration for group A and B was 13.4 ± 7.6 and 22.1 ± 9.2 months respectively. Device implantation was successful in all with an immediate closure rate of 95%. Rate of major complications were similar between the two groups but there were fewer minor complications in the surgical group. The duration of hospital stay (p value<0.001) and need for inotropes (p value<0.001) were significantly less in infants in group A.
Conclusion: Transcatheter device closure of large ductus in infants weighing less than 5 kg is possible with success rates comparable to surgical ligation. Appropriate patient selection and awareness of possible complications is essential.
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