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Fluctuating Amylase in a Female Child with Epilepsy and Global Developmental Delay and Absence of Pancreatitis

Aleysha C Cross, Chokanan Thaitirarot, Helen Jerina, Virginia Lee, Stephen Morley,Prashanth Patel, Pankaj Gupta and Hemant Bhavsar

Amylase is an enzyme produced by both the pancreas and salivary glands to digest carbohydrates. The enzyme is used as a marker for acute pancreatitis however amylase may also be raised in salivary gland disease and other intra-abdominal conditions. We report a case of raised and fluctuating amylase concentrations in the absence of pancreatic or salivary gland disease. Whilst amylase levels fluctuated, serum lipase remained in the normal range and radiological investigation showed no evidence of pancreatitis.