Анналы клинической нефрологии Открытый доступ

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Landscape of Kidney Tissue in Human Nephrotic Syndrome

Deepak Nihalani

Nephrotic syndrome is a rare disease of glomerular filtration barrier failurecausing massive urinary excretion of protein, that can progress to chronic kidney disease and end-stage renal disease NS is a heterogeneous disease, so we use the histologic descriptions ogf lomeruli on kidney biopsy to diagnose individuals with “minimal change disease ” and “focal segmental glomerulosclerosis .” Additionally, we use an individual’s response to these treatments to give them a post hoc diagnosis of steroid-sensitive NS or steroid-resistant NS