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Neuroleptic malignant syndrome presenting with self injurious behaviour

Raghavendra Bakki Sannegowda

Neuroleptic malignant syndrome is an emergency condition produced as an ill effect of certain drugs. Tetrad of symptoms includes fever, muscle rigidity, autonomic features, and altered mental status. Pathophysiology underlying this condition is dopamine receptor blockade or depletion of dopamine. Clear workup including identification of other systemic and neuropsychiatric conditions with overlapping symptoms is important for accurate diagnosis of this condition. Treatment includes immediate withdrawal of causative and use of dopamine agonists and muscle relaxants.