Aim: To study and compare the association between estimated GFR with cystatin-C and serum creatinine and the lipid profile in chronic kidney disease. Background: Chronic kidney disease (CKD) is frequently complicated by the coexistence of cardiovascular (CV) events, making it essential to identify CV risk in CKD. Serum cystatin-C is an upcoming renal biomarker, which is used to measure estimated glomerular filtration rate (eGFR) by the CKD-EPI formula.