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Quantification of Albendazole in Dewormer Formulations in the Kenyan market

H.N. Wanyika, P G Kareru, L M Gitu, E. G. Gatebe and B. N. Muyemba

In this study, the amount of active ingredient, Methyl [5-(propylthio)-2- benzimidazolecarbamate] (albendazole) in dewormer formulations was quantified using High Performance Liquid Chromatography (HPLC) and Ultra–Violet/ Visible (UV/ Vis) Spectrophotometer. Dewormer samples were obtained from various drug stores in Nairobi city. The analyses results indicated that in a number of cases the concentrations of albendazole differed with that indicated on the manufacturers’ labels. In two cases the concentration of albendazole grossly differed from other samples.