Ardeshir Zafari
Increment of serum concentration of Lipoprotein(a) [LP(a)] is an independent Coronary Artery Diseases (CAD) risk factor and clinical updates support of LP(a) roles in CAD. We assumed that appropriate and regular physical activity should be reduce the amount of LP(a) and thus reduce the risk of CAD; but research evidences indicated that LP(a) levels not been alter by physical activity and it is resistant to the exercise training stimulations. So, the serum concentration of LP(a) in active and sedentary middle age males is different? What is the effect of physical activity and exercise training on serum concentration of LP(a) in middle age males? The aim of this Cross-sectional study was to determine and compare of LP(a) serum concentration in selected groups of men (40-55 yrs). This descriptive study was designed in three groups of subjects who were voluntarily participated and randomly selected. Fasting serum concentration of LP(a) (Active: 18.06 ± 11.11; Sedentary: 22.06 ± 13.99; CAD: 28.33 ± 7.20 mg/dl) analysis with Immunoturbidimetric method. LP(a) compared with Kruskal-Wallis Ranks and Mann-Whitney (U) tests (P≤0.05). Results demonstrated that LP(a) differences between Active and CAD groups are significant (p=0.009). Study evidences and results of this study indicated that LP(a) levels not been alter by physical activity and it is resistant to the exercise training stimulations. If LP(a) changes was based on exercise training effects, these differences most are observed between active and sedentary groups, also; but in this study were not seen. Therefore to understanding the effects of exercises training and physical activity on LP(a), more study should be performed.
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