Hadis Alvandi, K. Salehzadeh, M. R. Najafzade and A. Taheri Kalani
Exercise training-induced increase in anti-inflammatory cytokines is one of methods proposed to reducing chronic inflammation. The purpose of the present study was to investigate the effects of 10 weeks strength training on plasma anti-inflammatory cytokines and their relationships with testosterone and cortisol hormone and body composition in youngs men. Nineteen sedentary men (age, 20-30 yr), volunteers to participant in the study, that randomly divided to two groups of strength training (n=10) and control (n=9) group. Blood sample were collected before and after 10 weeks from intervention, and the concentrations of plasma IL-4, IL-10 and testosterone were measured. Ten weeks strength training programme consists of 7 exercise in two sets with 8 repetitions at 70% of 1- RM in each exercise, and this is then as progressive changed to three sets with 8 repetitions at 80% of 1-RM in weeks 10. Dependent and independent t test, indicated that strength training increased upper and lower body strength, fat free mass, testosterone hormone and decreased cortisol hormone and body fat percent (P<0.05), but concentrations of plasma IL-4 and IL-10 not changed (P˃0.05). In addition, Pearson’s correlation indicated that no relationships were between changes in anti-inflammatory cytokines concentrations and changes in testosterone cortisol hormone and body composition (P˃0.05). These results indicated that despite significant improvement of strength and body composition, 10 weeks strength training did not effect on anti-inflammatory cytokines in young men.